Condition

Vascular intestinal disorders

Clinical trials and treatment information for Vascular intestinal disorders

169K
People Affected
80
Active Trials
14K
New Cases/Year
92K
Deaths/Year

Treatment Rankings

Ranked by evidence volume first. Medicine has spent centuries ranking things by vibes. This is an improvement.

1
Open Surgical Revascularization
90% Effectiveness• 85% Confidence• 40% Safety• 1 trials• 8K participants
MODERATE EvidenceModerate Value
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
40
DangerousModerateSafe

Time to Effect

Immediate

Duration

Single procedure, long-term monitoring

Response Rate

90%

Remission Rate

85%

Common Side Effects:

Surgical site infection: 10%
Bleeding: 7%
Myocardial infarction: 5%
Stroke: 2%
Renal failure: 3%

Annual Cost of Care

Drug Cost

$100

Monitoring

$800

Side Effects

$1,000

Total Annual

$1,900

Cost-Effectiveness

MODERATE

QALYs Gained

2.2

ICER

$95,000/QALY

Cost per Remission

$2,235

Cost per Responder

$2,111

Treatment Outcomes
Primary Outcomes
Post-prandial Abdominal Pain Intensity (VAS 0-10)VAS score: 7/10 (average after meals)
-70% (-4.9 points)
Body Weight48 kg (with documented >10% weight loss)
+15% (+7.2 kg)
Percentage of Caloric Intake from Parenteral Nutrition70% of daily caloric intake from PN
-85% (-59.5% (reduction in reliance on PN))
Secondary Benefits
Quality of Life (GIQLI - Gastrointestinal Quality of Life Index)GIQLI score: 70/144 (lower is worse)
+25% (+17.5 points)
Serum Albumin2.8 g/dL (indicating malnutrition)
+21% (+0.59 g/dL)
Functional Status (ECOG Performance Status)ECOG Performance Status: 3/5 (requiring assistance)
-66.7% (-2 points (e.g., from 3 to 1))
Common Side Effects
Surgical site infection
+10%
Bleeding
+7%
Myocardial infarction
+5%

Clinical Trial Phases:

Phase 4
2
Supportive Care (IV Fluids, Bowel Rest)
90% Effectiveness• 85% Confidence• 95% Safety00
HIGH EvidenceExcellent Value
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe

Time to Effect

Hours-days

Duration

3-7 days (acute episode)

Response Rate

85%

Remission Rate

85%

Common Side Effects:

Fluid overload (rare): 1%
Electrolyte imbalance (rare): 1%

Annual Cost of Care

Drug Cost

$100

Monitoring

$5,000

Side Effects

$100

Total Annual

$5,200

Cost-Effectiveness

EXCELLENT

QALYs Gained

0.5

Cost per Remission

$6,118

Cost per Responder

$6,118

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+85%
Remission Rate
+85%
Common Side Effects
Fluid overload (rare)
+1%
Electrolyte imbalance (rare)
+1%

Clinical Trial Phases:

Phase 4
3
Endovascular Revascularization (Angioplasty & Stenting)
85% Effectiveness• 80% Confidence• 50% Safety• 80 trials• 6K participants
MODERATE EvidenceGood Value
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe

Time to Effect

Immediate

Duration

Single procedure, long-term monitoring

Response Rate

85%

Remission Rate

75%

Common Side Effects:

Access site hematoma/bleeding: 7%
Stent restenosis: 15%
Contrast nephropathy: 7%

Annual Cost of Care

Drug Cost

$100

Monitoring

$700

Side Effects

$500

Total Annual

$1,300

Cost-Effectiveness

GOOD

QALYs Gained

2

ICER

$75,000/QALY

Cost per Remission

$1,733

Cost per Responder

$1,529

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+75%
Common Side Effects
Access site hematoma/bleeding
+7%
Stent restenosis
+15%
Contrast nephropathy
+7%

Clinical Trial Phases:

Phase 4
4
Papaverine (Intra-arterial)
85% Effectiveness• 75% Confidence• 50% Safety• 30 trials• 300 participants
LOW EvidenceExcellent ValueDose: 30-60 mg/hr intra-arterially
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe

Time to Effect

Minutes-hours

Duration

24-72 hours

Response Rate

75%

Remission Rate

%

Common Side Effects:

Hypotension: 5%
Cardiac arrhythmias: 2%
Local arterial complications: 3%

Annual Cost of Care

Drug Cost

$100

Monitoring

$8,000

Side Effects

$500

Total Annual

$8,600

Cost-Effectiveness

EXCELLENT

QALYs Gained

1.5

Cost per Responder

$11,467

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+75%
Common Side Effects
Hypotension
+5%
Cardiac arrhythmias
+2%
Local arterial complications
+3%

Clinical Trial Phases:

Phase 4
5
Anticoagulation (e.g., Rivaroxaban)
80% Effectiveness• 85% Confidence• 55% Safety• 150 trials• 30K participants
HIGH EvidenceExcellent ValueDose: Rivaroxaban 20mg daily
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe

Time to Effect

Hours-days

Duration

3-6 months to lifetime

Response Rate

80%

Remission Rate

%

Number Needed to Harm (NNH)

200

Common Side Effects:

Bleeding (major): 2%
Bleeding (minor): 15%

Annual Cost of Care

Drug Cost

$600

Monitoring

$200

Side Effects

$700

Total Annual

$1,500

Cost-Effectiveness

EXCELLENT

QALYs Gained

1.8

ICER

$40,000/QALY

Cost per Responder

$1,875

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+80%
Common Side Effects
Bleeding (major)
+2%
Bleeding (minor)
+15%

Clinical Trial Phases:

Phase 4
6
Broad-spectrum Antibiotics (e.g., Ciprofloxacin + Metronidazole)
70% Effectiveness• 70% Confidence• 70% Safety• 50 trials• 5K participants
MODERATE EvidenceExcellent ValueDose: Ciprofloxacin 400mg IV q12h + Metronidazole 500mg IV q8h
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe

Time to Effect

24-48 hours

Duration

7-14 days

Response Rate

65%

Remission Rate

%

Number Needed to Harm (NNH)

50

Common Side Effects:

Diarrhea (incl. C. difficile): 10%
Nausea/Vomiting: 5%
Allergic reactions: 2%

Annual Cost of Care

Drug Cost

$200

Monitoring

$500

Side Effects

$300

Total Annual

$1,000

Cost-Effectiveness

EXCELLENT

QALYs Gained

0.8

Cost per Responder

$1,538

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+65%
Common Side Effects
Diarrhea (incl. C. difficile)
+10%
Nausea/Vomiting
+5%
Allergic reactions
+2%

Clinical Trial Phases:

Phase 4
7
Antiplatelet Therapy (e.g., Aspirin)
65% Effectiveness• 85% Confidence• 80% Safety• 1000 trials• 100K participants
HIGH EvidenceExcellent ValueDose: Aspirin 81mg daily
Find Trials

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe

Time to Effect

Days

Duration

Lifetime

Response Rate

%

Remission Rate

%

Number Needed to Treat (NNT)

75

Number Needed to Harm (NNH)

300

Common Side Effects:

GI upset: 10%
Bleeding (GI): 2%

Annual Cost of Care

Drug Cost

$50

Monitoring

$50

Side Effects

$100

Total Annual

$200

Cost-Effectiveness

EXCELLENT

QALYs Gained

0.2

ICER

$15,000/QALY

Treatment Outcomes
Efficacy Outcomes
Overall Effectiveness
+65%
Common Side Effects
GI upset
+10%
Bleeding (GI)
+2%

Clinical Trial Phases:

Phase 4