Pembrolizumab

Treatment for Tracheal, bronchus, and lung cancer

Typical Dosage: 200 mg IV every 3 weeks or 400 mg IV every 6 weeks

Effectiveness
85%
Safety Score
35%
Clinical Trials
500
Participants
50K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
200 mg IV every 3 weeks or 400 mg IV every 6 weeks
Time to Effect
2-4 months
Treatment Duration
Up to 2 years or until disease progression/unacceptable toxicity
Evidence Quality
HIGH
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$180,000
Monitoring:$8,000
Side Effect Mgmt:$10,000
Total Annual:$198,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATE
ICER
$150,000/QALY
QALYs Gained
0.46
Outcome-Based Costs
Cost per Responder
$565,714
Cost per Remission
$3,960,000
Comparison vs Platinum-based Chemotherapy
Cost Difference
+$150,000/year
More expensive
QALY Difference
+0.46 QALYs
Better outcomes
Dominance
No dominance
Pembrolizumab Outcomes

for Tracheal, bronchus, and lung cancer

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+35%
Remission Rate
+5%
Common Side Effects
Fatigue
+40%
Nausea
+20%
Diarrhea
+20%
Pruritus
+20%
Rash
+20%
Hypothyroidism
+15%
Pneumonitis (immune-related)
+5%

Sources:

nih.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov