Tinnitus Retraining Therapy (TRT)
Treatment for Tinnitus
Typical Dosage: Daily use of sound generators for 6-12 hours, initial intensive counseling
Effectiveness
75%
Safety Score
95%
Clinical Trials
9
Participants
8K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Daily use of sound generators for 6-12 hours, initial intensive counseling
Time to Effect
6-18 months
Treatment Duration
12-24 months of consistent sound generator use and counseling
Evidence Quality
MODERATEConfidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$300
Side Effect Mgmt:$0
Total Annual:$4,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$25,000/QALY
QALYs Gained
0.07
Outcome-Based Costs
Cost per Responder
$6,923
Cost per Remission
$22,500
Tinnitus Retraining Therapy (TRT) Outcomes
for Tinnitus
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+65%
Remission Rate
+20%
Common Side Effects
Adjustment to sound generators
+10%
Initial frustration with therapy length
+8%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
2 active trials recruiting for Tinnitus Retraining Therapy (TRT) in Tinnitus
Oto Smartphone App in Treating Tinnitus Amongst Adult Patients Compared with Standard Talking Therapies
NCT06623123RECRUITINGPHASE3
160 participants
INTERVENTIONAL
Stevenage, United Kingdom
Started: Jun 20, 2024
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Tailor-Made Notched Music Training Therapy for Chronic Subjective Tinnitus
NCT07469969NOT YET RECRUITINGNA
386 participants
INTERVENTIONAL
Guangzhou, China
Started: Apr 1, 2026
Completed Clinical Trials
6 completed trials for Tinnitus Retraining Therapy (TRT) in Tinnitus
The Value of EMDR in the Treatment of Tinnitus
NCT03114878COMPLETEDNA
166 participants
INTERVENTIONAL
Edegem, Belgium
Started: Oct 1, 2016
Evaluation of Treatment Methods for Clinically Significant Tinnitus
NCT00013390COMPLETEDPHASE2
200 participants
INTERVENTIONAL
Portland, United States
Started: Oct 1, 1999
Multi-Site Randomized Clinical Study of Tinnitus Treatment Methods
NCT00235807COMPLETEDNA
144 participants
INTERVENTIONAL
Portland, United States
Started: Jun 1, 2004
Tinnitus Retraining Therapy Trial
NCT01177137COMPLETEDPHASE3
151 participants
INTERVENTIONAL
Camp Pendleton, United States +5 more
Started: Jul 1, 2011
The Effect of Transcranial Direct Current Stimulation (tDCS) in Addition to Tinnitus Retraining Therapy (TRT) for Treatment of Chronic Tinnitus Patients
NCT02285803COMPLETEDNA
INTERVENTIONAL
Edegem, Belgium
Started: Nov 1, 2014
Intervention for Reduced Sound Tolerance
NCT00890526COMPLETEDPHASE1
36 participants
INTERVENTIONAL
Baltimore, United States
Started: Jul 1, 2002