Magnesium Sulfate

Treatment for Tetanus

Typical Dosage: Loading dose (e.g., 4-5g IV) followed by continuous infusion (e.g., 2g/hour), titrated to effect and serum levels

Effectiveness
80%
Safety Score
55%
Clinical Trials
20
Participants
2K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Loading dose (e.g., 4-5g IV) followed by continuous infusion (e.g., 2g/hour), titrated to effect and serum levels
Time to Effect
Minutes to hours (after initiation of infusion)
Treatment Duration
Days to weeks (continuous infusion)
Evidence Quality
HIGH
Number Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$5,000
Side Effect Mgmt:$300
Total Annual:$5,330
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
8
Outcome-Based Costs
Cost per Responder
$7,107
Magnesium Sulfate Outcomes

for Tetanus

Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+75%
Common Side Effects
Hypotension
+25%
Respiratory depression
+15%
Bradycardia
+10%
Flushing
+5%

Sources:

nih.gov
researchgate.net
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov