Ibuprofen

Treatment for Tension Headache

Typical Dosage: 200-400 mg every 4-6 hours, max 1200 mg/day (OTC)

Effectiveness
68%
Safety Score
75%
Clinical Trials
5
Participants
75K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
200-400 mg every 4-6 hours, max 1200 mg/day (OTC)
Time to Effect
30-60 minutes
Treatment Duration
As needed for acute episodes
Evidence Quality
HIGH
Number Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Confidence Score
89%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$1,000
Side Effect Mgmt:$10
Total Annual:$1,040
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$61.54
Ibuprofen Outcomes

for Tension Headache

Efficacy Outcomes
Overall Effectiveness
+68%
Response Rate
+65%
Common Side Effects
Dyspepsia
+15%
Nausea
+6%
Abdominal pain
+6%

Sources:

aafp.org
thennt.com
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
3 completed trials for Ibuprofen in Tension Headache

Placebo and Active Controlled, Double Dummy Study to Compare Efficacy of Aspirin and Ibuprofen in Treatment of Episodic Tension-type Headache

NCT01464983COMPLETEDPHASE4
View Study
1.11K participants
INTERVENTIONAL
Reading, United Kingdom +10 more
Started: Jan 1, 2004

Ibuprofen Sodium Tension Headache Study

NCT01362491COMPLETEDPHASE3
View Study
226 participants
INTERVENTIONAL
Philadelphia, United States
Started: Jun 1, 2011

Study Evaluating A Novel Ibuprofen Formulation In Episodic Tension-Type Headache

NCT01077973COMPLETEDPHASE3
View Study
200 participants
INTERVENTIONAL
Started: Mar 1, 2010