Aspirin + Acetaminophen + Caffeine (Combination)
Treatment for Tension Headache
Typical Dosage: 2 tablets (250mg Aspirin, 250mg Acetaminophen, 65mg Caffeine) every 4-6 hours, max 8 tablets/day
Effectiveness
72%
Safety Score
72%
Clinical Trials
150
Participants
18K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
72
DangerousModerateSafe
Treatment Details
Dosage Range
2 tablets (250mg Aspirin, 250mg Acetaminophen, 65mg Caffeine) every 4-6 hours, max 8 tablets/day
Time to Effect
15-45 minutes
Treatment Duration
As needed for acute episodes (avoid overuse >2-3 days/week)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$1,000
Side Effect Mgmt:$20
Total Annual:$1,070
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$93.33
Aspirin + Acetaminophen + Caffeine (Combination) Outcomes
for Tension Headache
Efficacy Outcomes
Overall Effectiveness
+72%
Response Rate
+75%
Common Side Effects
Nausea
+8%
Dyspepsia
+7%
Nervousness/Insomnia
+10%
Rebound Headache (with overuse)
+15%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov