Metrifonate
Treatment for Schistosomiasis
Typical Dosage: 7.5-10 mg/kg body weight, three doses at 2-week intervals
Effectiveness
65%
Safety Score
60%
Clinical Trials
50
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
7.5-10 mg/kg body weight, three doses at 2-week intervals
Time to Effect
Rapid for parasite killing, weeks-months for symptom improvement
Treatment Duration
3 doses over 4 weeks
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$40
Side Effect Mgmt:$30
Total Annual:$85
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$800/QALY
QALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$113.33
Cost per Remission
$141.67
Comparison vs Praziquantel
Cost Difference
+$30/year
More expensive
QALY Difference
-0.30 QALYs
Worse outcomes
Dominance
No dominance
Metrifonate Outcomes
for Schistosomiasis
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+75%
Remission Rate
+60%
Common Side Effects
Abdominal pain
+30%
Nausea
+25%
Dizziness
+20%
Fatigue
+18%
Sweating
+7%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov