Adalimumab
Treatment for Rheumatoid arthritis
Typical Dosage: 40 mg every other week (subcutaneous)
Effectiveness
82%
Safety Score
42%
Clinical Trials
249
Participants
75K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
42
DangerousModerateSafe
Treatment Details
Dosage Range
40 mg every other week (subcutaneous)
Time to Effect
2-4 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
30(Treat 30 patients to see 1 additional serious adverse event)
Confidence Score
92%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$60,000
Monitoring:$1,500
Side Effect Mgmt:$1,000
Total Annual:$62,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$110,000/QALY
QALYs Gained
1.5
Outcome-Based Costs
Cost per Responder
$89,285.71
Cost per Remission
$208,333.33
Comparison vs Methotrexate
Cost Difference
+$60,900/year
More expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
No dominance
Adalimumab Outcomes
for Rheumatoid arthritis
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
18 completed trials for Adalimumab in Rheumatoid arthritis
Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis
NCT02114931COMPLETEDPHASE3
467 participants
INTERVENTIONAL
Huntsville, United States +76 more
Started: Apr 1, 2014
Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis
NCT01970475COMPLETEDPHASE3
526 participants
INTERVENTIONAL
Victorville, United States +10 more
Started: Oct 1, 2013
Efficacy and Safety of Adalimumab in Patients With Active Rheumatoid Arthritis Treated Concomitantly With Methotrexate.
NCT00195702COMPLETEDPHASE3
619 participants
INTERVENTIONAL
Huntsville, United States +86 more
Started: Feb 1, 2000
Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis
NCT01078571COMPLETED
705 participants
OBSERVATIONAL
A Coruña, Spain +39 more
Started: May 1, 2006
Pharmacokinetic and Safety Study With Adalimumab in Chinese Subjects With Mild Rheumatoid Arthritis
NCT00650156COMPLETEDPHASE1
24 participants
INTERVENTIONAL
Shanghai, China
Started: Jun 1, 2007
The Effect of Adalimumab (Humira) on Vascular Abnormalities in Rheumatoid Arthritis. A Pilot Study.
NCT01270087COMPLETEDPHASE4
14 participants
INTERVENTIONAL
Malmö, Sweden
Started: May 1, 2005
Real-World Outcome of Adalimumab on Rheumatoid Arthritis Patients in China
NCT02668640COMPLETED
55 participants
OBSERVATIONAL
Started: May 1, 2016
A Study to Compare Efficacy and Safety of CT-P17 With Humira in Patients With Active Rheumatoid Arthritis
NCT03789292COMPLETEDPHASE3
648 participants
INTERVENTIONAL
Sofia, Bulgaria
Started: Nov 26, 2018
A Study of Adalimumab When Added to Inadequate Standard Anti-rheumatic Therapy in Patients With Active Rheumatoid Arthritis
NCT01231321COMPLETEDPHASE3
100 participants
INTERVENTIONAL
Kazan', Russia +4 more
Started: Dec 1, 2007
A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients
NCT02405780COMPLETEDPHASE3
645 participants
INTERVENTIONAL
Peoria, United States +91 more
Started: Jun 10, 2015
Serum Concentration of Adalimumab as a Predictive Factor of Clinical Outcomes in Rheumatoid Arthritis (AFORA)
NCT01382160COMPLETEDPHASE4
69 participants
INTERVENTIONAL
Brest, France +6 more
Started: Jan 1, 2011
A Study of Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis
NCT00647491COMPLETEDPHASE2, PHASE3
352 participants
INTERVENTIONAL
Aichi, Japan +24 more
Started: Feb 1, 2004
Assessment of the Effect of Adalimumab on Response to Influenza Virus and Pneumococcal Vaccines in Subjects With Rheumatoid Arthritis
NCT00649922COMPLETEDPHASE4
226 participants
INTERVENTIONAL
Started: Oct 1, 2003
Post-marketing Observational Study in Subjects With Rheumatoid Arthritis
NCT00234884COMPLETED
3.44K participants
OBSERVATIONAL
Camperdown, Australia +310 more
Started: Sep 1, 2003
A Study Comparing LBAL to Humira® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy
NCT02746380COMPLETEDPHASE3
383 participants
INTERVENTIONAL
Tokyo, Japan +1 more
Started: Apr 13, 2016
A Study to Compare FKB327 Efficacy and Safety With Humira® in Rheumatoid Arthritis Patients
NCT02260791COMPLETEDPHASE3
728 participants
INTERVENTIONAL
Peoria, United States +99 more
Started: Dec 1, 2014
Self-injection of Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis
NCT00603993COMPLETEDPHASE3
88 participants
INTERVENTIONAL
Aichi, Japan +15 more
Started: Mar 1, 2006
Crossover Study of Safety and Tolerability of Two Formulations of Adalimumab.
NCT01561313COMPLETEDPHASE2
64 participants
INTERVENTIONAL
Genk, Belgium +5 more
Started: Mar 1, 2012
Showing 20 of 250 total trials