Warfarin
Treatment for Rheumatic heart disease
Typical Dosage: 1-10mg daily (INR adjusted)
Effectiveness
90%
Safety Score
55%
Clinical Trials
2
Participants
75K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
1-10mg daily (INR adjusted)
Time to Effect
3-5 days (to therapeutic INR)
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
40(Treat 40 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
150(Treat 150 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$440
Side Effect Mgmt:$150
Total Annual:$620
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$20,000/QALY
QALYs Gained
1
Outcome-Based Costs
Cost per Responder
$705
Warfarin Outcomes
for Rheumatic heart disease
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+88%
Common Side Effects
Minor bleeding (bruising, nosebleeds)
+10%
Major bleeding (GI, intracranial)
+3%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Warfarin in Rheumatic heart disease
INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority
NCT02832544COMPLETEDPHASE3
4.57K participants
INTERVENTIONAL
Gaborone, Botswana +138 more
Started: Aug 22, 2016