Oral Iron Supplementation (effective if iron deficient)
Treatment for Restless Legs Syndrome
Typical Dosage: Ferrous sulfate 325 mg daily or every other day (with Vitamin C)
Effectiveness
90%
Safety Score
85%
Clinical Trials
30
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
Ferrous sulfate 325 mg daily or every other day (with Vitamin C)
Time to Effect
4-12 weeks
Treatment Duration
3-6 months then maintenance
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$90
Monitoring:$400
Side Effect Mgmt:$20
Total Annual:$510
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$1,000/QALY
QALYs Gained
0.4
Outcome-Based Costs
Cost per Responder
$638
Cost per Remission
$1,020
Oral Iron Supplementation (effective if iron deficient) Outcomes
for Restless Legs Syndrome
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+80%
Remission Rate
+50%
Common Side Effects
Constipation
+20%
Nausea
+10%
Abdominal pain
+8%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov