Primary Cleft Palate Repair (Palatoplasty)

Treatment for Orofacial clefts

Effectiveness
88%
Safety Score
65%
Clinical Trials
4,000
Participants
400K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate anatomical closure, speech benefits over months-years
Treatment Duration
Single surgery (2-4 hours), 4-6 weeks recovery
Evidence Quality
HIGH
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$75
Monitoring:$2,000
Side Effect Mgmt:$1,000
Total Annual:$3,075
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
ICER
$97,500/QALY
QALYs Gained
1.8
Outcome-Based Costs
Cost per Responder
$3,342
Cost per Remission
$4,731
Primary Cleft Palate Repair (Palatoplasty) Outcomes

for Orofacial clefts

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+92%
Remission Rate
+65%
Common Side Effects
Oronasal fistula
+15%
Velopharyngeal insufficiency (VPI)
+25%
Speech difficulties
+70%
Wound infection
+2%
Bleeding
+1%

Sources:

who.int
nih.gov
asha.org

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov