Mitral Valve Replacement (Surgical)

Treatment for Non-rheumatic degenerative mitral valve disease

Effectiveness
88%
Safety Score
50%
Clinical Trials
1,200
Participants
400K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate symptom relief post-recovery (full recovery 3-6 months)
Treatment Duration
One-time procedure (lifelong anticoagulation for mechanical valve)
Evidence Quality
HIGH
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,000
Monitoring:$1,500
Side Effect Mgmt:$750
Total Annual:$3,250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$45,000/QALY
QALYs Gained
4
Outcome-Based Costs
Cost per Responder
$3,421.05
Cost per Remission
$3,611.11
Comparison vs Mitral Valve Repair
Cost Difference
+$10,000/year
More expensive
QALY Difference
-0.50 QALYs
Worse outcomes
Dominance
No dominance
Mitral Valve Replacement (Surgical) Outcomes

for Non-rheumatic degenerative mitral valve disease

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+95%
Remission Rate
+90%
Common Side Effects
Arrhythmias (e.g., Atrial Fibrillation)
+28%
Bleeding/Transfusion
+10%
Stroke
+2.5%
Infection
+3%
Acute Kidney Injury
+7%
In-hospital Mortality
+3.5%
Anticoagulation-related bleeding (with mechanical valve)
+2.5%
Bioprosthetic valve degeneration/re-operation
+15%

Sources:

amegroups.cn
nih.gov
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov