Surgical Aortic Valve Replacement (SAVR)
Treatment for Non-rheumatic calcific aortic valve disease
Effectiveness
92%
Safety Score
40%
Clinical Trials
800
Participants
200K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
40
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate hemodynamic improvement, symptomatic relief within weeks to months post-recovery
Treatment Duration
One-time procedure; valve durability 10-20+ years; initial procedure cost $25,000-$50,000.
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Confidence Score
98%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,500
Side Effect Mgmt:$1,200
Total Annual:$2,700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$70,000/QALY
QALYs Gained
1.6
Comparison vs Transcatheter Aortic Valve Replacement (TAVR)
Cost Difference
$-5,000/year
Less expensive
QALY Difference
-0.10 QALYs
Worse outcomes
Dominance
No dominance
Surgical Aortic Valve Replacement (SAVR) Outcomes
for Non-rheumatic calcific aortic valve disease
Efficacy Outcomes
Overall Effectiveness
+92%
Response Rate
+92%
Remission Rate
+99%
Common Side Effects
Major bleeding
+15%
Stroke
+2%
Acute kidney injury
+10%
Atrial fibrillation
+20%
Sternal wound infection
+3%
Prolonged recovery
+30%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov