Open Craniotomy for Hematoma Evacuation
Treatment for Intracerebral hemorrhage
Typical Dosage: Surgical procedure (depending on clot size and location)
Effectiveness
55%
Safety Score
25%
Clinical Trials
5
Participants
3K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
Surgical procedure (depending on clot size and location)
Time to Effect
Immediate post-op
Treatment Duration
Acute intervention, then rehabilitation
Evidence Quality
MODERATENumber Needed to Treat (NNT)
20(Treat 20 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
60%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$100,000
Side Effect Mgmt:$15,000
Total Annual:$115,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POORICER
$180,000/QALY
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$2,300,000
Open Craniotomy for Hematoma Evacuation Outcomes
for Intracerebral hemorrhage
Efficacy Outcomes
Overall Effectiveness
+55%
Response Rate
+5%
Common Side Effects
Infection
+8%
Neurological deficit worsening
+15%
Seizure
+10%
Hydrocephalus
+7%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
4 active trials recruiting for Open Craniotomy for Hematoma Evacuation in Intracerebral hemorrhage
Minimally Invasive Soft Channel Brain Haemorrhage Evacuation for Acute Basal Ganglia Haemorrhage-- Large Hemorrhage Evacuation (MIRACLE-L)
NCT06688201RECRUITINGNA
550 participants
INTERVENTIONAL
Linyi, China
Started: Jan 4, 2025
Early Minimally Invasive Image Guided Endoscopic Evacuation of Intracerebral Haemorrhage (EMINENT-ICH)
NCT05681988RECRUITINGNA
200 participants
INTERVENTIONAL
Basel, Switzerland +9 more
Started: Jan 1, 2024
Safety and Efficacy of Stereotactic Aspiration Plus Urokinase in Deep Intracerebral Hemorrhage Evacuation
NCT04686877RECRUITINGNA
400 participants
INTERVENTIONAL
Fuzhou, China
Started: Jan 31, 2021
RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH
NCT07205263RECRUITINGNA
1K participants
INTERVENTIONAL
Hangzhou, China
Started: Sep 30, 2025
Completed Clinical Trials
1 completed trial for Open Craniotomy for Hematoma Evacuation in Intracerebral hemorrhage
Minimally-invasive Surgery Versus Craniotomy in Patients With Supratentorial Hypertensive Intracerebral Hemorrhage
NCT02811614COMPLETEDNA
733 participants
INTERVENTIONAL
Beijing, China
Started: Jul 1, 2016