Cyclosporine

Treatment for Interstitial Cystitis

Typical Dosage: 2.5-3.5 mg/kg/day

Effectiveness
70%
Safety Score
35%
Clinical Trials
1
Participants
500

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
2.5-3.5 mg/kg/day
Time to Effect
1-3 months
Treatment Duration
6-12 months, or long-term if tolerated
Evidence Quality
MODERATE
Confidence Score
65%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$4,000
Monitoring:$2,400
Side Effect Mgmt:$1,000
Total Annual:$7,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POOR
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$10,571.43
Cost per Remission
$49,333.33
Cyclosporine Outcomes

for Interstitial Cystitis

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+70%
Remission Rate
+15%
Common Side Effects
Nephrotoxicity
+15%
Hypertension
+15%
Headache
+12%
Gingival hyperplasia
+8%
Increased infection risk
+7%

Sources:

nih.gov
spandidos-publications.com
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Cyclosporine in Interstitial Cystitis

Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action

NCT01990898COMPLETEDPHASE2
View Study
26 participants
INTERVENTIONAL
Cleveland, United States
Started: Nov 1, 2013