Amitriptyline
Treatment for Interstitial Cystitis
Typical Dosage: 10-100mg daily
Effectiveness
60%
Safety Score
58%
Clinical Trials
3
Participants
4K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
58
DangerousModerateSafe
Treatment Details
Dosage Range
10-100mg daily
Time to Effect
4-8 weeks
Treatment Duration
Lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$500
Side Effect Mgmt:$100
Total Annual:$800
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$52,865/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$1,777.78
Cost per Remission
$16,000
Amitriptyline Outcomes
for Interstitial Cystitis
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+45%
Remission Rate
+5%
Common Side Effects
Dry mouth
+40%
Drowsiness
+30%
Constipation
+15%
Weight gain
+15%
Dizziness
+12%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
1 active trial recruiting for Amitriptyline in Interstitial Cystitis
EA for BPS: An RCT and Study for Central Mechanism
NCT05279963RECRUITINGNA
84 participants
INTERVENTIONAL
Hangzhou, China
Started: Mar 16, 2022
Completed Clinical Trials
1 completed trial for Amitriptyline in Interstitial Cystitis
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
NCT00124306COMPLETEDPHASE3
271 participants
INTERVENTIONAL
Stanford, United States +9 more
Started: Feb 1, 2005