Doxepin (low-dose)
Treatment for Insomnia
Typical Dosage: 3-6 mg at bedtime
Effectiveness
60%
Safety Score
60%
Clinical Trials
35
Participants
7.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
3-6 mg at bedtime
Time to Effect
1-2 hours
Treatment Duration
long-term
Evidence Quality
HIGHNumber Needed to Treat (NNT)
10(Treat 10 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
40(Treat 40 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$75
Monitoring:$150
Side Effect Mgmt:$20
Total Annual:$245
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$445
Cost per Remission
$3,062
Doxepin (low-dose) Outcomes
for Insomnia
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+55%
Remission Rate
+8%
Common Side Effects
Somnolence
+5%
Nausea
+2%
Dizziness
+2%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov