Levetiracetam
Treatment for Idiopathic epilepsy
Typical Dosage: 500-3000 mg daily
Effectiveness
80%
Safety Score
60%
Clinical Trials
4
Participants
60K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
60
DangerousModerateSafe
Treatment Details
Dosage Range
500-3000 mg daily
Time to Effect
Days to weeks
Treatment Duration
Lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,000
Monitoring:$500
Side Effect Mgmt:$300
Total Annual:$1,800
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
6
Outcome-Based Costs
Cost per Responder
$3,600
Cost per Remission
$5,143
Levetiracetam Outcomes
for Idiopathic epilepsy
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+50%
Remission Rate
+35%
Common Side Effects
Somnolence/Fatigue
+18%
Irritability/Agitation
+15%
Dizziness
+12%
Headache
+10%
Anorexia
+8%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
4 completed trials for Levetiracetam in Idiopathic epilepsy
Levetiracetam Versus Valproate in Idiopathic Generalized Tonic-clonic Seizures
NCT03940326COMPLETEDPHASE4
103 participants
INTERVENTIONAL
Sari, Iran
Started: Apr 1, 2018
Levetiracetam Versus Valproate in Idiopathic Generalized Epilepsy
NCT06393309COMPLETED
169 participants
OBSERVATIONAL
Sari, Iran
Started: Sep 3, 2022
Study to Evaluate the Safety and Efficacy of Levetiracetam in Patients Suffering From Idiopathic Generalized Epilepsy With Primary Generalized Tonic-clonic Seizures
NCT00160550COMPLETEDPHASE3
154 participants
INTERVENTIONAL
Started: Sep 1, 2001
Levetiracetam as add-on Treatment of Myoclonic Jerks in Adolescents + Adults
NCT00150774COMPLETEDPHASE3
116 participants
INTERVENTIONAL
Started: Nov 1, 2001