Lamotrigine
Treatment for Idiopathic epilepsy
Typical Dosage: 100-500 mg daily
Effectiveness
75%
Safety Score
65%
Clinical Trials
350
Participants
55K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
65
DangerousModerateSafe
Treatment Details
Dosage Range
100-500 mg daily
Time to Effect
Weeks to months
Treatment Duration
Lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
9(Treat 9 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
12(Treat 12 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$900
Monitoring:$400
Side Effect Mgmt:$200
Total Annual:$1,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
5
Outcome-Based Costs
Cost per Responder
$3,333
Cost per Remission
$4,286
Lamotrigine Outcomes
for Idiopathic epilepsy
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+45%
Remission Rate
+35%
Common Side Effects
Dizziness
+15%
Ataxia
+8%
Rash (including serious SJS/TEN)
+7%
Nausea
+6%
Headache
+6%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov