Radioactive Iodine (I-131) Therapy

Treatment for Hyperthyroidism

Typical Dosage: 3-30 mCi (millicuries)

Effectiveness
90%
Safety Score
35%
Clinical Trials
1
Participants
100K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
3-30 mCi (millicuries)
Time to Effect
6 weeks to 6 months
Treatment Duration
Single dose, lifelong monitoring and levothyroxine if hypothyroidism develops
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$750
Monitoring:$600
Side Effect Mgmt:$100
Total Annual:$1,450
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$40,000/QALY
QALYs Gained
1
Outcome-Based Costs
Cost per Responder
$1,611
Cost per Remission
$1,611
Radioactive Iodine (I-131) Therapy Outcomes

for Hyperthyroidism

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Remission Rate
+90%
Common Side Effects
Hypothyroidism (expected outcome, requires lifelong levothyroxine)
+85%
Transient worsening of hyperthyroidism
+5%
Thyroiditis/neck pain
+5%
Dry mouth/eyes
+1%

Sources:

nih.gov
oup.com
researchgate.net

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov