Trichloroacetic Acid (TCA)

Treatment for HPV Infection

Typical Dosage: 80-90% solution, applied weekly

Effectiveness
80%
Safety Score
80%
Clinical Trials
4
Participants
6K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
80-90% solution, applied weekly
Time to Effect
1-4 weeks per session
Treatment Duration
Multiple sessions over 4-12 weeks
Evidence Quality
HIGH
Number Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,000
Side Effect Mgmt:$50
Total Annual:$1,050
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
Outcome-Based Costs
Cost per Responder
$1,312.5
Cost per Remission
$1,312.5
Comparison vs Cryotherapy
Cost Difference
$0/year
Same cost
QALY Difference
0.00 QALYs
Same outcomes
Dominance
No dominance
Trichloroacetic Acid (TCA) Outcomes

for HPV Infection

Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+80%
Remission Rate
+80%
Common Side Effects
Local pain
+80%
Burning sensation
+60%
Ulceration
+40%
Scarring
+7%

Sources:

nih.gov
fortunejournals.com
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
3 completed trials for Trichloroacetic Acid (TCA) in HPV Infection

Efficacy and Safety of TCA vs. ECA for the Treatment of AIN in HIV-positive Patients

NCT02615860COMPLETEDNA
View Study
560 participants
INTERVENTIONAL
Essen, Germany
Started: Nov 1, 2015

The Effect of Oral Nanocurcumin as an Adjuvant Therapy for Anogenital Warts: Evaluation of Clinical Improvement, NFĸB, IFN-γ, and FOXP3+TReg From Lesions Tissue

NCT06281353COMPLETEDPHASE2, PHASE3
View Study
78 participants
INTERVENTIONAL
Jakarta Pusat, Indonesia
Started: Aug 16, 2022

Typing of Human Papilloma Virus (HPV) From Female Genital Warts

NCT01192282COMPLETED
View Study
156 participants
OBSERVATIONAL
Cape Town, South Africa
Started: Apr 1, 2010