Gemifloxacin + Azithromycin (Dual Therapy, Oral Alternative)
Treatment for Gonococcal infection
Typical Dosage: Gemifloxacin 320mg oral + Azithromycin 2g oral
Effectiveness
92%
Safety Score
60%
Clinical Trials
18
Participants
2.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
Gemifloxacin 320mg oral + Azithromycin 2g oral
Time to Effect
1-3 days
Treatment Duration
Single dose
Evidence Quality
MODERATENumber Needed to Treat (NNT)
1.4(Treat 1.4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
4(Treat 4 patients to see 1 additional serious adverse event)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$160
Monitoring:$150
Side Effect Mgmt:$100
Total Annual:$410
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEQALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$446
Cost per Remission
$446
Comparison vs Ceftriaxone + Azithromycin
Cost Difference
+$215/year
More expensive
QALY Difference
-0.04 QALYs
Worse outcomes
Dominance
No dominance
Gemifloxacin + Azithromycin (Dual Therapy, Oral Alternative) Outcomes
for Gonococcal infection
Efficacy Outcomes
Overall Effectiveness
+92%
Response Rate
+92%
Remission Rate
+92%
Common Side Effects
Diarrhea (Azithromycin 2g)
+20%
Nausea (Azithromycin 2g)
+12%
Rash (Gemifloxacin)
+5%
Tendon rupture (Gemifloxacin, rare)
+0.05%
Peripheral neuropathy (Gemifloxacin, rare)
+0.05%
Sources:
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov