Misoprostol
Treatment for Gastritis and duodenitis
Typical Dosage: 100-200 mcg two to four times daily
Effectiveness
65%
Safety Score
58%
Clinical Trials
200
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
58
DangerousModerateSafe
Treatment Details
Dosage Range
100-200 mcg two to four times daily
Time to Effect
Days for symptom relief, continuous for prevention
Treatment Duration
As long as NSAIDs are used, or for specific indications
Evidence Quality
MODERATENumber Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
4(Treat 4 patients to see 1 additional serious adverse event)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$480
Monitoring:$50
Side Effect Mgmt:$50
Total Annual:$580
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$50,000/QALY
QALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$828
Cost per Remission
$1,055
Comparison vs Omeprazole (PPI)
Cost Difference
+$310/year
More expensive
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
Misoprostol Outcomes
for Gastritis and duodenitis
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+70%
Remission Rate
+55%
Common Side Effects
Diarrhea
+25%
Abdominal pain
+15%
Nausea
+5%
Uterine contractions (contraindicated in pregnancy)
+1%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov