Folic Acid Supplementation

Treatment for G6PD deficiency

Typical Dosage: 1 mg daily

Effectiveness
85%
Safety Score
90%
Clinical Trials
50
Participants
10K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
90
DangerousModerateSafe
Treatment Details
Dosage Range
1 mg daily
Time to Effect
Weeks to months (to normalize folate levels and support erythropoiesis)
Treatment Duration
Lifetime (for patients with chronic hemolysis)
Evidence Quality
MODERATE
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$10
Monitoring:$1,500
Side Effect Mgmt:$0
Total Annual:$1,510
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$100/QALY
QALYs Gained
0.05
Comparison vs No folate supplementation
Cost Difference
$-10/year
Less expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Folic Acid Supplementation Outcomes

for G6PD deficiency

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+100%
Common Side Effects
Nausea
+0.1%
Bloating
+0.1%

Sources:

aafp.org
clinicalodyssey.com
medscape.com

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov