Cycloserine / Terizidone (as part of regimens)
Treatment for Extensively drug-resistant tuberculosis
Typical Dosage: 250-1000mg daily
Effectiveness
58%
Safety Score
40%
Clinical Trials
20
Participants
1.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
40
DangerousModerateSafe
Treatment Details
Dosage Range
250-1000mg daily
Time to Effect
3-6 months
Treatment Duration
18-24 months
Evidence Quality
LOWConfidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$2,000
Side Effect Mgmt:$3,000
Total Annual:$5,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$60,000/QALY
QALYs Gained
0.4
Outcome-Based Costs
Cost per Responder
$9,455
Cost per Remission
$9,455
Comparison vs Less effective older XDR-TB regimens
Cost Difference
+$1,000/year
More expensive
QALY Difference
+0.15 QALYs
Better outcomes
Dominance
No dominance
Cycloserine / Terizidone (as part of regimens) Outcomes
for Extensively drug-resistant tuberculosis
Efficacy Outcomes
Overall Effectiveness
+58%
Response Rate
+55%
Remission Rate
+55%
Common Side Effects
Psychiatric disturbances (anxiety, depression, psychosis)
+35%
Seizures
+7%
Peripheral neuropathy
+12%
Headache/Dizziness
+20%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov