Punctal Plugs (Silicone or dissolvable)
Treatment for Dry Eye Disease
Typical Dosage: 1-4 plugs per patient
Effectiveness
70%
Safety Score
85%
Clinical Trials
25
Participants
3.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
1-4 plugs per patient
Time to Effect
immediate
Treatment Duration
temporary (dissolvable) or permanent (silicone)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$300
Side Effect Mgmt:$100
Total Annual:$500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$833
Cost per Remission
$3,333
Comparison vs Artificial Tears
Cost Difference
$-100/year
Less expensive
QALY Difference
+0.04 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Punctal Plugs (Silicone or dissolvable) Outcomes
for Dry Eye Disease
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+60%
Remission Rate
+15%
Common Side Effects
Foreign body sensation
+10%
Epiphora (excessive tearing)
+5%
Plug extrusion
+15%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov