PAIR (Puncture, Aspiration, Injection, Re-aspiration) Monotherapy

Treatment for Cystic echinococcosis

Effectiveness
88%
Safety Score
60%
Clinical Trials
35
Participants
3.5K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate cyst drainage, clinical improvement within weeks, full resolution 6-12 months
Treatment Duration
Single procedure (often followed by short course of albendazole, but not included in 'monotherapy' efficacy)
Evidence Quality
HIGH
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$750
Monitoring:$1,500
Side Effect Mgmt:$200
Total Annual:$12,450
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
Outcome-Based Costs
Cost per Responder
$14,647
Cost per Remission
$15,563
Comparison vs Surgical Excision
Cost Difference
$-20,800/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
DOMINATESBetter + cheaper
PAIR (Puncture, Aspiration, Injection, Re-aspiration) Monotherapy Outcomes

for Cystic echinococcosis

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+85%
Remission Rate
+80%
Common Side Effects
Local pain/discomfort
+15%
Anaphylaxis (due to scolex spillage)
+3%
Bile leakage
+1%
Secondary infection
+1%

Sources:

researchgate.net
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov