PAIR (Puncture, Aspiration, Injection, Re-aspiration) + Albendazole

Treatment for Cystic echinococcosis

Typical Dosage: Albendazole 10-15 mg/kg/day in two divided doses

Effectiveness
90%
Safety Score
58%
Clinical Trials
40
Participants
4K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
58
DangerousModerateSafe
Treatment Details
Dosage Range
Albendazole 10-15 mg/kg/day in two divided doses
Time to Effect
Initial improvement within weeks, full resolution 6-12 months
Treatment Duration
Single procedure, albendazole for 3-6 months (pre/post-PAIR)
Evidence Quality
HIGH
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,500
Monitoring:$1,500
Side Effect Mgmt:$400
Total Annual:$13,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
Outcome-Based Costs
Cost per Responder
$14,889
Cost per Remission
$16,750
Comparison vs Surgical Excision
Cost Difference
$-19,850/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
No dominance
PAIR (Puncture, Aspiration, Injection, Re-aspiration) + Albendazole Outcomes

for Cystic echinococcosis

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Remission Rate
+80%
Common Side Effects
Local pain/discomfort
+15%
Anaphylaxis (from spillage)
+3%
Elevated liver enzymes
+15%
Gastrointestinal upset
+10%
Leukopenia
+5%

Sources:

nih.gov
nih.gov
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov