Modafinil

Treatment for Cocaine use disorders

Typical Dosage: 100-400mg daily

Effectiveness
50%
Safety Score
65%
Clinical Trials
25
Participants
1.5K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
100-400mg daily
Time to Effect
1-2 weeks
Treatment Duration
3-6 months
Evidence Quality
LOW
Number Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1000(Treat 1000 patients to see 1 additional serious adverse event)
Confidence Score
60%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,000
Monitoring:$100
Side Effect Mgmt:$50
Total Annual:$1,150
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POOR
ICER
$200,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$2,875
Cost per Remission
$5,750
Modafinil Outcomes

for Cocaine use disorders

Efficacy Outcomes
Overall Effectiveness
+50%
Response Rate
+40%
Remission Rate
+20%
Common Side Effects
Headache
+18%
Insomnia
+12%
Nausea
+8%
Anxiety
+5%

Sources:

nih.gov
uconn.edu
tandfonline.com

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov