Lithium
Treatment for Cluster Headache
Typical Dosage: 600-1200 mg/day (titrated to serum levels)
Effectiveness
75%
Safety Score
30%
Clinical Trials
18
Participants
1.1K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
30
DangerousModerateSafe
Treatment Details
Dosage Range
600-1200 mg/day (titrated to serum levels)
Time to Effect
1-2 weeks
Treatment Duration
Months to years
Evidence Quality
MODERATENumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$240
Monitoring:$900
Side Effect Mgmt:$200
Total Annual:$1,340
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$2,436
Lithium Outcomes
for Cluster Headache
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+55%
Common Side Effects
Tremor
+25%
Polyuria/Polydipsia
+25%
Nausea
+15%
Weight gain
+15%
Hypothyroidism
+8%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov