Lisinopril

Treatment for Chronic kidney disease due to diabetes mellitus type 2

Typical Dosage: Lisinopril 10-40mg daily

Effectiveness
90%
Safety Score
70%
Clinical Trials
1,000
Participants
2M

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
Lisinopril 10-40mg daily
Time to Effect
1-2 months for albuminuria reduction, 6-12 months for sustained eGFR benefit
Treatment Duration
lifetime
Evidence Quality
HIGH
Number Needed to Treat (NNT)
15(Treat 15 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
98%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$180
Monitoring:$1,200
Side Effect Mgmt:$75
Total Annual:$1,455
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$20,000/QALY
QALYs Gained
1.5
Outcome-Based Costs
Cost per Responder
$1,711.76
Lisinopril Outcomes

for Chronic kidney disease due to diabetes mellitus type 2

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+85%
Common Side Effects
Cough
+10%
Hyperkalemia
+5%
Hypotension
+3%

Sources:

oup.com
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov