Amitriptyline

Treatment for Chronic Fatigue Syndrome

Typical Dosage: 10-50mg at bedtime

Effectiveness
45%
Safety Score
60%
Clinical Trials
12
Participants
750

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
10-50mg at bedtime
Time to Effect
2-4 weeks
Treatment Duration
Long-term
Evidence Quality
MODERATE
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$200
Side Effect Mgmt:$75
Total Annual:$375
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$25,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$1,250
Cost per Remission
$18,750
Amitriptyline Outcomes

for Chronic Fatigue Syndrome

Efficacy Outcomes
Overall Effectiveness
+45%
Response Rate
+30%
Remission Rate
+2%
Common Side Effects
Dry mouth
+35%
Drowsiness/Sedation
+25%
Constipation
+20%
Weight gain
+15%
Dizziness
+12%

Sources:

nih.gov
meassociation.org.uk
moregooddays.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov