Amoxicillin-Clavulanate

Treatment for Cellulitis

Typical Dosage: 500mg/125mg orally every 8 hours or 875mg/125mg orally every 12 hours

Effectiveness
88%
Safety Score
70%
Clinical Trials
3
Participants
45K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
500mg/125mg orally every 8 hours or 875mg/125mg orally every 12 hours
Time to Effect
1-2 days
Treatment Duration
7 days
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$25
Monitoring:$125
Side Effect Mgmt:$20
Total Annual:$170
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$188.89
Cost per Remission
$200
Prescription Access Economics
Annual Societal Loss per Patient
$1,735
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$150/year
Time Cost
$50/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$25/year
Potential OTC Price
$10/year
Estimated if OTC available
Early Treatment Benefit
+0.01 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
HIGH
Missed Diagnosis Risk
MODERATE
Amoxicillin-Clavulanate Outcomes

for Cellulitis

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+90%
Remission Rate
+85%
Common Side Effects
Diarrhea
+12%
Nausea
+7%
Abdominal pain
+3%
Rash
+1%

Sources:

hopkinsguides.com
droracle.ai
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
2 completed trials for Amoxicillin-Clavulanate in Cellulitis

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

NCT00368537COMPLETEDPHASE4
View Study
550 participants
INTERVENTIONAL
Scottsdale, United States +56 more
Started: Sep 1, 2006

A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections

NCT00249197COMPLETEDPHASE3
View Study
413 participants
INTERVENTIONAL
Started: Jan 1, 1997