Venlafaxine (SNRI)
Treatment for Anxiety Disorder
Typical Dosage: 75-225mg daily
Effectiveness
75%
Safety Score
60%
Clinical Trials
4
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
60
DangerousModerateSafe
Treatment Details
Dosage Range
75-225mg daily
Time to Effect
2-4 weeks
Treatment Duration
6-12 months, often longer
Evidence Quality
HIGHNumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
9(Treat 9 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$400
Monitoring:$200
Side Effect Mgmt:$120
Total Annual:$720
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$55,000/QALY
QALYs Gained
0.23
Outcome-Based Costs
Cost per Responder
$1,309
Cost per Remission
$2,400
Comparison vs No Treatment
Cost Difference
+$720/year
More expensive
QALY Difference
+0.23 QALYs
Better outcomes
Dominance
No dominance
Venlafaxine (SNRI) Outcomes
for Anxiety Disorder
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+55%
Remission Rate
+30%
Common Side Effects
Nausea
+25%
Dizziness
+15%
Sweating
+18%
Sexual dysfunction
+25%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
3 completed trials for Venlafaxine (SNRI) in Anxiety Disorder
Effectiveness of Long-Term Versus Short-Term Treatment of Generalized Anxiety Disorder With Venlafaxine XR
NCT00183274COMPLETEDPHASE4
268 participants
INTERVENTIONAL
Philadelphia, United States
Started: Jan 1, 2004
Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions
NCT04478526COMPLETEDNA
115 participants
INTERVENTIONAL
Kingston, Canada
Started: Apr 29, 2020
Anxiety and Depression in Epilepsy: A Treatment Study
NCT03464383COMPLETEDPHASE4
69 participants
INTERVENTIONAL
Winston-Salem, United States
Started: May 7, 2018