Duloxetine (SNRI)

Treatment for Anxiety Disorder

Typical Dosage: 30-120mg daily

Effectiveness
72%
Safety Score
60%
Clinical Trials
3
Participants
20K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
30-120mg daily
Time to Effect
2-4 weeks
Treatment Duration
6-12 months, often longer
Evidence Quality
HIGH
Number Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
11(Treat 11 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$450
Monitoring:$200
Side Effect Mgmt:$100
Total Annual:$750
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
ICER
$60,000/QALY
QALYs Gained
0.22
Outcome-Based Costs
Cost per Responder
$1,500
Cost per Remission
$2,679
Comparison vs No Treatment
Cost Difference
+$750/year
More expensive
QALY Difference
+0.22 QALYs
Better outcomes
Dominance
No dominance
Duloxetine (SNRI) Outcomes

for Anxiety Disorder

Efficacy Outcomes
Overall Effectiveness
+72%
Response Rate
+50%
Remission Rate
+28%
Common Side Effects
Nausea
+20%
Dry mouth
+15%
Constipation
+10%
Insomnia
+10%

Sources:

nih.gov
nih.gov
dovepress.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

FIX IT
Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
2 completed trials for Duloxetine (SNRI) in Anxiety Disorder

Duloxetine for Social Anxiety Disorder: Prediction of Long Term Outcome

NCT00114127COMPLETEDPHASE3
View Study
28 participants
INTERVENTIONAL
Boston, United States
Started: Jun 1, 2004

Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions

NCT04478526COMPLETEDNA
View Study
115 participants
INTERVENTIONAL
Kingston, Canada
Started: Apr 29, 2020