Leukotriene Receptor Antagonists (LTRAs)

Treatment for Allergic Rhinitis

Typical Dosage: 10mg once daily (e.g., Montelukast)

Effectiveness
65%
Safety Score
55%
Clinical Trials
200
Participants
30K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
10mg once daily (e.g., Montelukast)
Time to Effect
1-2 weeks
Treatment Duration
Seasonal or daily as needed
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
2000(Treat 2000 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$180
Monitoring:$25
Side Effect Mgmt:$10
Total Annual:$215
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATE
QALYs Gained
0.02
Outcome-Based Costs
Cost per Responder
$430
Cost per Remission
$3,071.43
Comparison vs Intranasal Corticosteroids
Cost Difference
$0/year
Same cost
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
Prescription Access Economics
Leukotriene Receptor Antagonists (LTRAs) Outcomes

for Allergic Rhinitis

Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+50%
Remission Rate
+7%
Common Side Effects
Headache
+12%
Gastrointestinal upset
+7%
Neuropsychiatric events
+0.5%

Sources:

nih.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov