Suramin

Treatment for African trypanosomiasis

Typical Dosage: Test dose 100-200 mg IV, then 20 mg/kg IV on days 1, 3, 7, 14, 21

Effectiveness
95%
Safety Score
55%
Clinical Trials
1
Participants
3K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Test dose 100-200 mg IV, then 20 mg/kg IV on days 1, 3, 7, 14, 21
Time to Effect
Within days, full effect after treatment completion
Treatment Duration
5-7 weeks
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$400
Monitoring:$1,500
Side Effect Mgmt:$200
Total Annual:$2,100
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
3.5
Outcome-Based Costs
Cost per Responder
$2,211
Cost per Remission
$2,333
Suramin Outcomes

for African trypanosomiasis

Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+95%
Remission Rate
+90%
Common Side Effects
Renal toxicity
+15%
Peripheral neuropathy
+7%
Hypersensitivity reactions
+5%
Nausea
+20%
Fever
+25%

Sources:

cdc.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Suramin in African trypanosomiasis

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

NCT06060600COMPLETED
View Study
345 participants
OBSERVATIONAL
Tarrytown, United States
Started: Jan 2, 2023