Pentamidine

Treatment for African trypanosomiasis

Typical Dosage: 4 mg/kg IM or IV daily for 7-10 days

Effectiveness
95%
Safety Score
60%
Clinical Trials
1
Participants
5K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
4 mg/kg IM or IV daily for 7-10 days
Time to Effect
Within days, full effect after treatment completion
Treatment Duration
7-10 days
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$700
Side Effect Mgmt:$100
Total Annual:$1,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
3.5
Outcome-Based Costs
Cost per Responder
$1,053
Cost per Remission
$1,111
Pentamidine Outcomes

for African trypanosomiasis

Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+95%
Remission Rate
+90%
Common Side Effects
Hypotension
+40%
Hypoglycemia
+20%
Nephrotoxicity
+7%
Abdominal pain
+15%

Sources:

mdpi.com
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Pentamidine in African trypanosomiasis

Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

NCT00803933COMPLETEDPHASE2
View Study
111 participants
INTERVENTIONAL
Gombé, Republic of the Congo +1 more
Started: Feb 1, 2003