Ibuprofen
Treatment for Upper respiratory infections
Typical Dosage: 200-400mg every 4-6 hours (max 1200mg/day OTC)
Effectiveness
80%
Safety Score
75%
Clinical Trials
9
Participants
150K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
200-400mg every 4-6 hours (max 1200mg/day OTC)
Time to Effect
30-60 minutes
Treatment Duration
As needed, 3-7 days for URI symptoms
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1500(Treat 1500 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$10
Monitoring:$600
Side Effect Mgmt:$0
Total Annual:$610
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.008
Outcome-Based Costs
Cost per Responder
$11.11
Ibuprofen Outcomes
for Upper respiratory infections
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+90%
Common Side Effects
Stomach upset/nausea
+10%
Heartburn
+5%
Headache
+3%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
1 active trial recruiting for Ibuprofen in Upper respiratory infections
Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine
NCT06531707RECRUITINGPHASE3
177 participants
INTERVENTIONAL
Mexico City, Mexico
Started: May 20, 2024
Completed Clinical Trials
6 completed trials for Ibuprofen in Upper respiratory infections
The Efficacy and Safety of Dexibuprofen Syrup
NCT00812422COMPLETEDPHASE3
260 participants
INTERVENTIONAL
Seoul, South Korea +3 more
Started: Feb 1, 2008
Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection
NCT03918135COMPLETEDPHASE4
200 participants
INTERVENTIONAL
Denizli, Turkey (Türkiye)
Started: Jan 1, 2019
Acute Sore Throat Pain Study
NCT01535079COMPLETEDPHASE2
186 participants
INTERVENTIONAL
Gières, France +3 more
Started: Feb 1, 2012
Ibuprofen Lozenge in Acute Sore Throat Pain
NCT01785862COMPLETEDPHASE3
427 participants
INTERVENTIONAL
Gières, France +13 more
Started: Feb 1, 2013
Bioequivalence Study of Ibuprofen 200 mg + Pseudoephedrine HCL 30 mg Tablets Under Fed Conditions
NCT01132222COMPLETEDPHASE1
34 participants
INTERVENTIONAL
Bangalore, India
Started: Sep 1, 2004
Bioequivalency Study of Ibuprofen 200 mg and Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's Under Fasting Conditions
NCT01131780COMPLETEDPHASE1
32 participants
INTERVENTIONAL
Bangalore, India
Started: Oct 1, 2004