Alvimopan
Treatment for Paralytic ileus and intestinal obstruction
Typical Dosage: 12 mg orally pre-surgery, then 12 mg twice daily for up to 7 days
Effectiveness
75%
Safety Score
65%
Clinical Trials
25
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
12 mg orally pre-surgery, then 12 mg twice daily for up to 7 days
Time to Effect
1-2 days
Treatment Duration
Up to 7 days
Evidence Quality
HIGHNumber Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$2,500
Monitoring:$800
Side Effect Mgmt:$50
Total Annual:$3,350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$20,000/QALY
QALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$3,923
Comparison vs Standard Post-operative Care
Cost Difference
$-1,000/year
Less expensive
QALY Difference
+0.03 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Alvimopan Outcomes
for Paralytic ileus and intestinal obstruction
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+65%
Common Side Effects
Dyspepsia
+5%
Hypokalemia
+3%
Anemia
+2%
Urinary retention
+2%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov