Dimethyl Sulfoxide (DMSO)
Treatment for Interstitial Cystitis
Typical Dosage: 50mL of 50% solution intravesically
Effectiveness
65%
Safety Score
75%
Clinical Trials
5
Participants
2K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
50mL of 50% solution intravesically
Time to Effect
1-4 weeks
Treatment Duration
6-8 weeks induction, then maintenance
Evidence Quality
MODERATEConfidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$500
Side Effect Mgmt:$0
Total Annual:$6,800
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$11,353/QALY
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$12,363.64
Cost per Remission
$136,000
Dimethyl Sulfoxide (DMSO) Outcomes
for Interstitial Cystitis
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+55%
Remission Rate
+5%
Common Side Effects
Garlic-like body odor
+80%
Bladder discomfort
+40%
Bladder irritation
+15%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Dimethyl Sulfoxide (DMSO) in Interstitial Cystitis
Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC
NCT05223244COMPLETEDPHASE4
83 participants
INTERVENTIONAL
Started: Oct 1, 2011
Comparison of the Treatment of Refractory Bladder Pain Syndrome With DMSO and DMSO With Botulinum Toxin A
NCT03103594COMPLETEDEARLY_PHASE1
2 participants
INTERVENTIONAL
Started: Aug 1, 2015