Cefixime + Azithromycin (Dual Therapy, Oral Alternative)
Treatment for Gonococcal infection
Typical Dosage: Cefixime 800mg oral + Azithromycin 1g oral
Effectiveness
93%
Safety Score
70%
Clinical Trials
85
Participants
11K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
Cefixime 800mg oral + Azithromycin 1g oral
Time to Effect
1-3 days
Treatment Duration
Single dose
Evidence Quality
MODERATENumber Needed to Treat (NNT)
1.3(Treat 1.3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$40
Monitoring:$150
Side Effect Mgmt:$30
Total Annual:$220
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.04
Outcome-Based Costs
Cost per Responder
$236
Cost per Remission
$236
Comparison vs Ceftriaxone + Azithromycin
Cost Difference
+$25/year
More expensive
QALY Difference
-0.03 QALYs
Worse outcomes
Dominance
No dominance
Cefixime + Azithromycin (Dual Therapy, Oral Alternative) Outcomes
for Gonococcal infection
Efficacy Outcomes
Overall Effectiveness
+93%
Response Rate
+93%
Remission Rate
+93%
Common Side Effects
Diarrhea (Cefixime)
+18%
Nausea (Cefixime)
+7%
Abdominal pain (Cefixime)
+5%
Diarrhea (Azithromycin)
+14%
Headache
+2%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov