Blood Transfusion (for acute severe hemolysis)
Treatment for G6PD deficiency
Typical Dosage: Varies by patient's hemoglobin level and clinical status
Effectiveness
90%
Safety Score
65%
Clinical Trials
0
Participants
0
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
65
DangerousModerateSafe
Treatment Details
Dosage Range
Varies by patient's hemoglobin level and clinical status
Time to Effect
Immediate (within hours of administration)
Treatment Duration
As needed during acute hemolytic crisis (typically 1-2 units over several hours)
Evidence Quality
HIGHConfidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,500
Side Effect Mgmt:$0
Total Annual:$1,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
5
Comparison vs No blood transfusion during severe crisis
Cost Difference
$0/year
Same cost
QALY Difference
+5.00 QALYs
Better outcomes
Dominance
No dominance
Blood Transfusion (for acute severe hemolysis) Outcomes
for G6PD deficiency
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+95%
Common Side Effects
Febrile non-hemolytic transfusion reaction
+1%
Allergic reaction
+0.5%
Delayed hemolytic transfusion reaction
+0.05%
Transfusion-associated circulatory overload (TACO)
+0.05%
Transfusion-related acute lung injury (TRALI)
+0.01%
Infection (e.g., HIV, HCV, HBV)
+0.0001%
Sources:
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov