Acyclovir
Treatment for Encephalitis
Typical Dosage: 10 mg/kg IV every 8 hours
Effectiveness
90%
Safety Score
70%
Clinical Trials
4
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
70
DangerousModerateSafe
Treatment Details
Dosage Range
10 mg/kg IV every 8 hours
Time to Effect
Days
Treatment Duration
14-21 days intravenously
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$10,000
Side Effect Mgmt:$500
Total Annual:$11,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
8
Outcome-Based Costs
Cost per Responder
$15,714
Cost per Remission
$36,667
Acyclovir Outcomes
for Encephalitis
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+70%
Remission Rate
+30%
Common Side Effects
Nausea
+3%
Headache
+3%
Renal impairment
+2%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Acyclovir in Encephalitis
Impact of Obesity on Clinical Outcomes in Patients Receiving Acyclovir for HSV Encephalitis"
NCT05127395COMPLETED
50 participants
OBSERVATIONAL
Dallas, United States
Started: Mar 9, 2021
Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir
NCT00031486COMPLETEDPHASE3
91 participants
INTERVENTIONAL
Birmingham, United States +20 more
Started: Sep 1, 2000