Diphtheria Antitoxin (DAT)
Treatment for Diphtheria
Typical Dosage: 20,000-120,000 units IV/IM
Effectiveness
95%
Safety Score
50%
Clinical Trials
1
Participants
7.5K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
50
DangerousModerateSafe
Treatment Details
Dosage Range
20,000-120,000 units IV/IM
Time to Effect
Immediate
Treatment Duration
Single administration (can be repeated)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$2,000
Monitoring:$30,000
Side Effect Mgmt:$1,000
Total Annual:$33,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
15
Outcome-Based Costs
Cost per Responder
$38,823
Cost per Remission
$47,143
Diphtheria Antitoxin (DAT) Outcomes
for Diphtheria
Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+85%
Remission Rate
+70%
Common Side Effects
Serum sickness
+10%
Anaphylaxis
+5%
Local injection site reactions
+25%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Diphtheria Antitoxin (DAT) in Diphtheria
Post Marketing Surveillance of Diphtheria Antitoxin (DAT)
NCT06053853COMPLETEDPHASE4
68 participants
INTERVENTIONAL
Surabaya, Indonesia
Started: Jan 31, 2023