Negative Pressure Wound Therapy (NPWT)
Treatment for Decubitus ulcer
Typical Dosage: Continuous or intermittent negative pressure (e.g., -75 to -125 mmHg)
Effectiveness
82%
Safety Score
80%
Clinical Trials
19
Participants
18K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
Continuous or intermittent negative pressure (e.g., -75 to -125 mmHg)
Time to Effect
Visible changes in wound bed in days, healing weeks-months
Treatment Duration
Weeks to months
Evidence Quality
HIGHNumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
30(Treat 30 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$500
Side Effect Mgmt:$300
Total Annual:$8,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$50,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$10,000
Cost per Remission
$12,307.69
Negative Pressure Wound Therapy (NPWT) Outcomes
for Decubitus ulcer
Efficacy Outcomes
Overall Effectiveness
+82%
Response Rate
+80%
Remission Rate
+65%
Common Side Effects
Pain
+10%
Bleeding
+5%
Periwound skin damage
+7%
Infection
+4%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
4 active trials recruiting for Negative Pressure Wound Therapy (NPWT) in Decubitus ulcer
NPWTi on Closure of Chronic Pressure Sores
NCT05598398RECRUITINGPHASE4
62 participants
INTERVENTIONAL
Chicago, United States
Started: Sep 26, 2022
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
NCT06328010ENROLLING BY INVITATION
5K participants
OBSERVATIONAL
Scottsdale, United States +11 more
Started: Apr 1, 2024
Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries
NCT05496296RECRUITINGNA
300 participants
INTERVENTIONAL
San Diego, United States +13 more
Started: Apr 30, 2023
A Real-World Registry of Chronic Wounds and Ulcers
NCT02280733RECRUITING
300K participants
OBSERVATIONAL
The Woodlands, United States
Started: Jan 1, 2005
Completed Clinical Trials
7 completed trials for Negative Pressure Wound Therapy (NPWT) in Decubitus ulcer
Confirm Safety and Performance of Avance Solo and Avance Solo Adapt NPWT Systems
NCT04753294COMPLETEDNA
136 participants
INTERVENTIONAL
Ghent, Belgium +12 more
Started: Jun 14, 2021
Evaluating Blast-X® in Combination With Negative Pressure Wound Therapy
NCT04265170COMPLETEDNA
20 participants
INTERVENTIONAL
Kittanning, United States
Started: Oct 24, 2019
Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries
NCT03283787COMPLETEDNA
60 participants
INTERVENTIONAL
Jacksonville, United States
Started: Apr 1, 2017
The Study of Wound Dressings for Portable NPWT
NCT03135964COMPLETEDNA
57 participants
INTERVENTIONAL
Tainan, Taiwan
Started: Feb 1, 2011
Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers
NCT01022216COMPLETEDPHASE2
30 participants
INTERVENTIONAL
Brooklyn, United States
Started: Aug 1, 2009
Effectiveness of Negative-Pressure Wound Therapy
NCT04311229COMPLETEDNA
30 participants
INTERVENTIONAL
Started: Oct 13, 2016
A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System
NCT04593693COMPLETEDNA
25 participants
INTERVENTIONAL
Augusta, United States +1 more
Started: Dec 10, 2020