Endoscopic Sinus Surgery (ESS)

Treatment for Chronic Sinusitis

Effectiveness
88%
Safety Score
60%
Clinical Trials
12
Participants
10K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Time to Effect
4-8 weeks
Treatment Duration
one-time procedure (with ongoing medical therapy)
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$300
Monitoring:$500
Side Effect Mgmt:$100
Total Annual:$2,900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$10,000/QALY
QALYs Gained
0.4
Outcome-Based Costs
Cost per Responder
$3,625
Cost per Remission
$7,250
Comparison vs Maximal Medical Therapy
Cost Difference
+$2,000/year
More expensive
QALY Difference
+0.30 QALYs
Better outcomes
Dominance
No dominance
Endoscopic Sinus Surgery (ESS) Outcomes

for Chronic Sinusitis

Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+80%
Remission Rate
+40%
Common Side Effects
Post-operative pain
+85%
Nasal crusting
+40%
Minor bleeding
+15%
Infection
+3%

Sources:

nih.gov
researchgate.net
southcarolinablues.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

FIX IT
Active Clinical Trials
2 active trials recruiting for Endoscopic Sinus Surgery (ESS) in Chronic Sinusitis

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

NCT02975310RECRUITINGNA
View Study
140 participants
INTERVENTIONAL
Vancouver, Canada +3 more
Started: Apr 11, 2017

A Study Evaluating the Efficacy of Endoscope Ethmoid Infundibulum Expansion Surgery (EEIES) Combined With Stapokibart in the Treatment of Type 2 Chronic Rhinosinusitis

NCT07073664ENROLLING BY INVITATIONNA
View Study
30 participants
INTERVENTIONAL
Changchun, China
Started: Apr 21, 2025
Completed Clinical Trials
5 completed trials for Endoscopic Sinus Surgery (ESS) in Chronic Sinusitis

Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data

NCT05983003COMPLETED
View Study
3.5K participants
OBSERVATIONAL
Wuhan, China
Started: Mar 1, 2015

Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)

NCT03704415COMPLETEDNA
View Study
97 participants
INTERVENTIONAL
Helsinki, Finland +2 more
Started: Oct 23, 2018

Balloon Sinus Dilation In Office or OR

NCT00939393COMPLETEDNA
View Study
72 participants
INTERVENTIONAL
Independence, United States
Started: Apr 1, 2008

Efficacy of PuraSinus Versus Bioresorbable Nasal Dressings

NCT04970966COMPLETEDNA
View Study
30 participants
INTERVENTIONAL
Los Angeles, United States
Started: Jan 1, 2022

Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study

NCT01255566COMPLETED
View Study
186 participants
OBSERVATIONAL
Chicago, United States +2 more
Started: Aug 1, 2009