Prednisone (Corticosteroid)
Treatment for Chronic kidney disease due to glomerulonephritis
Typical Dosage: 0.5-1 mg/kg/day (initial), tapered
Effectiveness
75%
Safety Score
50%
Clinical Trials
200
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
0.5-1 mg/kg/day (initial), tapered
Time to Effect
days-weeks for anti-inflammatory effects
Treatment Duration
3-6 months (induction), then taper
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$500
Side Effect Mgmt:$1,000
Total Annual:$1,550
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
1.2
Outcome-Based Costs
Cost per Responder
$2,214
Cost per Remission
$3,100
Comparison vs No immunosuppression
Cost Difference
+$1,550/year
More expensive
QALY Difference
+1.20 QALYs
Better outcomes
Dominance
No dominance
Prednisone (Corticosteroid) Outcomes
for Chronic kidney disease due to glomerulonephritis
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+70%
Remission Rate
+50%
Common Side Effects
Weight gain/fluid retention
+60%
Hyperglycemia/diabetes
+30%
Hypertension
+20%
Insomnia/mood changes
+15%
Osteoporosis (long-term)
+15%
Infections
+10%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov