Mycophenolate Mofetil (MMF)
Treatment for Chronic kidney disease due to glomerulonephritis
Typical Dosage: 1-2 g orally twice daily
Effectiveness
78%
Safety Score
35%
Clinical Trials
100
Participants
15K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
35
DangerousModerateSafe
Treatment Details
Dosage Range
1-2 g orally twice daily
Time to Effect
1-3 months
Treatment Duration
1-3 years or more
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$3,000
Monitoring:$800
Side Effect Mgmt:$700
Total Annual:$4,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$80,000/QALY
QALYs Gained
1.4
Outcome-Based Costs
Cost per Responder
$6,618
Cost per Remission
$11,250
Comparison vs Cyclophosphamide (maintenance)
Cost Difference
+$500/year
More expensive
QALY Difference
+0.20 QALYs
Better outcomes
Dominance
No dominance
Mycophenolate Mofetil (MMF) Outcomes
for Chronic kidney disease due to glomerulonephritis
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+68%
Remission Rate
+40%
Common Side Effects
Gastrointestinal (diarrhea, nausea)
+30%
Leukopenia/anemia
+15%
Infections
+15%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov