Doxycycline
Treatment for Cellulitis
Typical Dosage: 100mg orally twice daily
Effectiveness
85%
Safety Score
70%
Clinical Trials
2
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanideβ οΈ
Methπ
Cigarettesπ¬
Chemoβ’οΈ
AlcoholπΊ
Morphineπ
Antibioticsπ
Tylenolπ
Exerciseπ
Waterπ§
70
DangerousModerateSafe
Treatment Details
Dosage Range
100mg orally twice daily
Time to Effect
1-2 days
Treatment Duration
7 days
Evidence Quality
HIGHConfidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$125
Side Effect Mgmt:$15
Total Annual:$155
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$182.35
Cost per Remission
$193.75
Prescription Access Economics
Annual Societal Loss per Patient
$1,730
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$150/year
Time Cost
$50/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$15/year
Potential OTC Price
$5/year
Estimated if OTC available
Early Treatment Benefit
+0.01 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
HIGHMissed Diagnosis Risk
MODERATEDoxycycline Outcomes
for Cellulitis
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+80%
Common Side Effects
Photosensitivity
+15%
Nausea
+7%
Vomiting
+7%
Diarrhea
+7%
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Doxycycline in Cellulitis
Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment
NCT03637400COMPLETEDPHASE2
269 participants
INTERVENTIONAL
Sylmar, United States +2 more
Started: Nov 26, 2018
A Prospective Trial of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Methicillin Resistant Staphylococcus Aureus Infections
NCT01049438COMPLETEDNA
31 participants
INTERVENTIONAL
Started: Aug 1, 2006